Sodium Hyaluronate is a great skin-identical ingredient with cell-communicating abilities. It has many scientifically proven benefits for skin including the fact that it improves the appearance of fine lines and wrinkles, reduces inflammation, is an antioxidant, retains moisture better than most other ingredients, strengthens skin barrier function, repairs wounds, regenerates skins, helps rebuild collagen, and is compatible with all skin types. A 2011 study by Pavicic et al. concluded that topical application of low molecular weight Sodium Hyaluronate formulations led to significant improvement in skin hydration and elasticity as well as significant reduction in wrinkle depth. A similar study found that nano-hyaluronic acid has significant benefits for decreasing the depth of wrinkles (up to 40%), skin hydration (up to 96%) and skin firmness and elasticity were significantly enhanced (up to 55%) at the end of eight weeks.
W. Y. John Chen and Giovanni Abatangelo; Wound Repair and Regeneration, International Journal of Wound Repair and Regeneration, 1999, 7: 79–89. Also available: http://onlinelibrary.wiley.com/enhanced/doi/10.1046/j.1524-475X.1999.00079.x/
S Manjula Jegasothy, Valentina Zabolotniaia, Stephan Bielfeldt. Efficacy of a New Topical Nano-hyaluronic Acid in Humans. J Clin Aesthet Dermatol 2014 Mar;7(3):27-29 .
Schlesinger T, Rowland P.; Efficacy and safety of a low-molecular weight hyaluronic Acid topical gel in the treatment of facial seborrheic dermatitis. J Clin Aesthet Dermatol. 2012;5(10):20-3.
Pavicic T, Gauglitz G, Lersch P, Schwach-Abdellaoui K, Malle B, Korting H, Farwick M.; Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment.